Last edited by Vulabar
Wednesday, August 12, 2020 | History

4 edition of Gene Therapy of Cancer found in the catalog.

Gene Therapy of Cancer

Translational Approaches From Preclinical Studies to Clinical Implementation (1st Edition)

  • 35 Want to read
  • 25 Currently reading

Published by Academic Press .
Written in English

    Subjects:
  • Genetics (non-medical),
  • Medical research,
  • therapy,
  • Immunotherapy,
  • Cancer Prevention,
  • Genetic Intervention,
  • Medical / Nursing,
  • Oncology,
  • Medical,
  • Neoplasms,
  • Genetics,
  • Cancer,
  • Gene therapy

  • Edition Notes

    ContributionsStanton L. Gerson (Editor), Edmund C., Ph.D. Lattime (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages406
    ID Numbers
    Open LibraryOL9282494M
    ISBN 100124371906
    ISBN 109780124371903

    The Most Comprehensive, State-of-the-Art Book on Using Gene and Cell Therapy in Clinical Medicine Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fourth Edition presents extensive background and basic information, state-of-the-art technologies, important achievements, and lingering challenges in the fields of gene and cell therapies. gene therapy listen (jeen THAYR-uh-pee) A type of experimental treatment in which foreign genetic material (DNA or RNA) is inserted into a person's cells to prevent or fight disease. Gene therapy is being studied in the treatment of certain types of cancer.

      CAR-T gene therapy is a new treatment recently approved for use by the FDA for some forms of leukemia and non-Hodgkin lymphoma. Dimas Padilla—a stage 4 . Gene therapy uses sections of DNA (usually genes) to treat or prevent disease.; The DNA is carefully selected to correct the effect of a mutated gene that is causing disease. The technique was first developed in but has, so far, had limited success in treating human diseases.

      Gene Therapy. A new gene therapy drug named Zoglensma became the most expensive drug in the world, costing patients over $ million for one-time use. Zoglensma joins a small (and outlandishly expensive) group of treatments called gene therapy drugs. Gene therapy uses actual genes to treat or prevent diseases. The book provides a comprehensive overview of the current state, and the new concepts for the future directions of modern cancer therapy. Bringing together all the relevant aspects from basic and applied science, and the clinical experiences of this new direction in medicine, it is an up-to-date summary of the activities in the field and will be the basis for evaluating future progress in this.


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Gene Therapy of Cancer Download PDF EPUB FB2

The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, Gene Therapy of Cancer book and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells.

Gene therapy alters the genetic instructions within an individual’s cells. A gene is a sequence of DNA — pictured above. A variety of efforts are underway to apply gene therapy to cancer treatment. Most are in early, exploratory stages, where they’re. The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer.

The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific basis of gene. Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics.

Emphasis is placed on the molecular bases of drug action, both applied and experimental. Vol GeneTherapy, features important new research on gene transfers and therapy in the herpes simplex virus, anti-tumor immunity, steroid receptors, cystic fibroses, and Features* It provides an.

Gene Therapy for cancer includes references up to and including This reflects the period of time that it takes to complete a multi-authored book. One criticism is that as cancer gene therapy is a rapidly advancing technology, the developments of the last 3 years in this field are : S Schepelmann, C J Springer.

Despite the hope that gene therapy can be used to treat cancer, genetic diseases, and AIDS, there are concerns that the immune system may attack cells treated by gene therapy, that the viral vectors could mutate and become virulent, or that altered genes might be passed to succeeding generations.

In a few instances trials have been halted when. From the reviews of the second edition: “This book, authored by a number of prominent researchers in the field provides an overview of recent ground-breaking experimental and clinical concepts and protocols in cancer gene therapy. the editors and authors are to be commended for producing a well-organised, authoritative and succinct coverage of the vast area of gene therapy protocols.

Gene transfer, while a radical new type of treatment, is also the only gene therapy product to obtain regulatory approval in any global market, as demonstrated by China’s approval of Gendicine for clinical use. 76 Gendicine is a modified adenovirus that delivers the p53 gene to cancer cells and is approved for the treatment of head and Cited by: “The Gene Therapy Plan is a comprehensive and practical approach to the science of epigenetics—and how to apply it to your life right now.

This book is a godsend that could save your life.” —Christiane Northrup, M.D., author of the New York Times bestseller Women’s Bodies, Women’s Wisdom/5(). Numerous cancer gene therapy strategies are currently being investigated, including gene replacement therapy, the regulation of gene expression to modulate immu- logical responses to tumors, the direct killing of tumor cells, and direct int- ference with tumor growth.5/5(1).

Advances in Cell and Gene Therapy is an international journal publishing original, high-quality, peer-reviewed articles which cover basic and clinical research relating to advances in cell, gene, and immune therapies and their use in the treatment of nonmalignant and neoplastic hematological diseases, as well as some non-hematological diseases.

The topics the journal covers include. Gene therapy has the potential to be a tailor-made therapeutic with increased specificity and decreased side effects that can offer a "cure" for many disorders. The aim of this book is to provide up-to-date reviews of the rapidly growing field of gene therapy.

Chapters cover a large range of topics including methods of gene delivery, and identification of targets with several papers on cancer Cited by: 8. The book has 67 contributors, mostly based in the United States.

It contains over pages of text, divided into three parts: (1) vectors used in gene therapy against cancer, (2) targets and Author: S Schepelmann, C J Springer. A type of integrating gene therapy, known as CAR-T therapies, has already been approved to treat patients with certain kinds of leukemia and lymphoma.

An integrating gene therapy to treat CF is being tested in animals, and a clinical trial to test the safety of this therapy in people with CF could happen in the next several years. Gene Therapy of Cancer: Methods and Protocols offers basic and clinical researchers a broad ranging overview and collection of the most recent advances in gene transfer techniques.

Written by leading international authorities, its readily reproducible, cutting-edge methods constitute today's most valuable tools for the study of cancer gene. Gene faults and cancer. Many gene changes that make a cell become cancerous are caused by environmental or lifestyle factors.

A small numberof people have inherited faulty genes that increase their risk of particular types of cancer. Read more about genes and inherited cancer risk; What gene therapy is. The Promise of Gene Therapy Unfolds In many ways, was the year of gene therapy in the United States.

Patients and pharmaceutical companies celebrated the approval of not one, but three treatments for otherwise untreatable health conditions. Researchers have been working on developing safe, effective gene therapies for three decades.

Early trials were plagued [ ]. The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer.

The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific basis of gene Book Edition: 2.

Viral Therapy of Cancer is essential reading for both basic scientists and clinicians with an interest in viral therapy and gene therapy. Reviews "The book is easy to read and is likely to be consulted by students, experienced researchers and medical practitioners alike.". Although gene therapy is a promising treatment option for a number of diseases (including inherited disorders, some types of cancer, and certain viral infections), the technique remains risky and is still under study to make sure that it will be safe and effective.

Gene therapy is currently being tested only for diseases that have no other cures. New Gene Therapy Produces Hope for a New Era in Cancer Treatment Written by Ann Pietrangelo on J Gene-altering therapy on the cusp of Author: Ann Pietrangelo.

Advancements in human genomics over the last two decades have shown that cancer is mediated by somatic aberration in the host genome. This discovery has incited enthusiasm among cancer researchers; many now use therapeutic approaches in genetic manipulation to improve cancer regression and find a potential cure for the disease.

Such gene therapy includes transferring genetic material into Cited by: The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer.

Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing.